We are physical scientists interested in developing and applying a range of new quantitative biophysical methods, based on laser fluorescence spectroscopy and scanning probe microscopy, to important problems in biology, which have not been addressed to date due to the lack of suitable tools and hence  directly image biological processes down to  the level of single molecules. While our experiments range from studies of individual biomolecules to living cells, no previous biological background is required for our research and we work closely with a range of biological and clinical collaborators. We are also part of the Cambridge Dementia Research centre.