PRINCIPAL INVESTIGATOR

David Klenerman

Professor Sir David Klenerman

David Klenerman's research is focused on developing and applying biophysical methods to biological and biomedical problems. His work using fluorescence and scanning probe microscopy has provided new insights into a variety of biomolecular complexes as well as the processes of protein folding and misfolding. David has also developed techniques to image individual protein complexes on the surface of living cells to follow the processes occurring as the adaptive immune response is triggered. These methods are now being used to study neurodegenerative disease.

David is a research fellow at the Royal Society, a fellow at the Academy of Medical Sciences and a fellow at Christ's College.

POSTDOCTORAL RESEARCHERS

 
Dr Anna Lippert

Dr Anna Lippert

I am Anna, a 4th year PhD student working on a joint-project between David Klenerman and the Immunology Group of Simon Davis in Oxford, studying the molecular mechanisms of Superagonism. I consider myself as an immunologically interested microscope monkey. In short: I like to play with lasers to ...

Dr Evgenia Lobanova

Dr Evgenia Lobanova

Evgenia obtained her BSc degree in Physics from Moscow State University in 2012. In 2014, she received her MSc degree in Physics from the same university. Soon after graduation, Evgenia moved to Cardiff where in 2019 she completed her PhD degree (Oct. 2015 – Oct. 201...

Dr John Danial

Dr John Danial

John is a postdoctoral research fellow designing and constructing high-throughput super resolution microscopy to characterize protein aggregates. Prior to joining the Klenerman lab at the University of Cambridge, John worked in the group of Professor Ana Garcia-Saez at the University of Tubingen ...

Dr. Matthew R. Cheetham

Dr. Matthew R. Cheetham

Matthew currently works on the development of a sensitive assay for early diagnosis of neurodegenerative diseases from blood serum. He completed his PhD at the University of Leeds in 2012 with Prof. Steve Evans, looking at the manipulation of lipid membranes with electric fields. After this, he w...

Dr Eleni Dimou

Dr Eleni Dimou

I completed my PhD studies at the University of Heidelberg in Germany working on a collaborative project between the groups of Prof. Walter Nickel (University of Heidelberg) and Prof. Helge Ewers (Free University of Berlin). My research focused on visualizing the unconventional secretion of FGF2 ...

Dr James McColl

Dr James McColl

James was awarded his PhD from the University of Cranfield in 2007, examining how molecules feel. He then joined the Klenerman group at the University of Cambridge as a postdoctoral researcher to investigate early T cell triggering mechanisms. Following a brief break to study cardiomyocyte migrat...

Dr Linda Julian

Dr Linda Julian

Linda was awarded her PhD from the University of Glasgow in 2015 for investigating the role of apoptotic membrane blebbing in tissue homeostasis and tumour development, working at Cancer Research UK Beatson Institute. She then joined as a postdoctoral research associate at the University of ...

PH.D STUDENTS

 
Bing Li

Bing Li

Bing is a first year PhD student in David Klenerman's group working on Light-sheet microscopy and Scanning ion conductance microscopy. He obtained his Bachel...

Dimitrios Sideris

Dimitrios Sideris

I'm an AstraZeneca-sponsored PhD student working on the preclinical testing of passive immunotherapies against Alzheimer's disease. I am particularly interes...

Emre Fertan

Emre Fertan

I completed my undergraduate and MSc degrees in neuroscience at Dalhousie University, Canada - studying behavioural and neurophysiological deficits in rodent...

Jane Humphrey

Jane Humphrey

Jane studied biochemistry in Bristol before coming to Cambridge on the Wellcome Trust studentship. She's passionate about applying quantitative met...

Jonathan X. Meng

Jonathan X. Meng

I am a second year PhD student at Professor Klenerman's lab, contributing my effort to our understanding of Alzheimer’s disease ontology. I completed my...

Markus Körbel

Markus Körbel

Markus is a PhD student investigating the early activation processes of T cells; a project in collaboration with the Immunology Lab of Simon Davis in Oxford....

Yunzhao Wu

Yunzhao Wu

I’m a first-year Ph.D. student working on elucidating the mechanisms of p53 aggregation in cancer with super-resolution imaging. I graduated from Shanghai Ji...

Ziwei Zhang

Ziwei Zhang

I am a first year PhD student on a joint-project between the Klenerman’s group and the Laue group in the Department of Biochemistry at Cambridge. I will be w...

Derya Emin

Derya Emin

I am a 1st year PhD student at Clare and I am interested in the size-dependent characterisation of α-synuclein. My mornings usually start at 6 am when I get ...

Dorothea Böken

Dorothea Böken

Dorothea joined the Klenerman group as a PhD student in January 2021. Her work focuses on studying protein aggregates in Parkinson’s disease. After completin...

Helen Henson

Helen Henson

I work in a collaborative project between the Department of Clinical Neurosciences and Department of Chemistry to directly image protein aggregates, tau and ...

Jeff Lam

Jeff Lam

Jeff is a PhD student investigating the interactions between protein aggregates and small molecules under super-resolution microscopy. He was brought up in H...

Klara Kulenkampff

Klara Kulenkampff

I am a joint PhD student between the KlenermanLab and the group of Prof. Michele Vendruscolo developing rationally designed antibodies against tau aggregates...

Yu Zhang

Yu Zhang

I am a first year PhD student working on developing advanced single molecule techniques towards in-depth research of the molecular basis of major neurogenera...

Zengjie Xia

Zengjie Xia

Zengjie (aka Ronald) is an AstraZeneca sponsored PhD student working on characterising the binding of MEDI1341 with α-synuclein using multiple ultra-sensitiv...

 
 
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