PRINCIPAL INVESTIGATOR
Professor Sir David Klenerman
David Klenerman's research is focused on developing and applying biophysical methods to biological and biomedical problems. His work using fluorescence and scanning probe microscopy has provided new insights into a variety of biomolecular complexes as well as the processes of protein folding and misfolding. David has also developed techniques to image individual protein complexes on the surface of living cells to follow the processes occurring as the adaptive immune response is triggered. These methods are now being used to study neurodegenerative disease.
David is a research fellow at the Royal Society, a fellow at the Academy of Medical Sciences and a fellow at Christ's College.
POSTDOCTORAL RESEARCHERS
Dr Bing Li
Bing is a postdoctoral researcher in David Klenerman's group working on Light-sheet microscopy and Scanning ion conductance microscopy. He obtained his Bachelor's degree in Southern University of Science and Technology in China and Master's degree in University of Cambridge. Now as a PhD student,...
Dr Dezerae Cox
Dr Dezerae Cox is a Research Fellow working to uncover the fundamental drivers Motor Neuron Disease. Her work focuses on the application of novel single-molecule super-resolution microscopy and proteomics methods to characterise protein aggregates from disease-derived tissues and biofluids. Dezer...
Dr Jeff Lam
Jeff is a postdoctoral researcher who applies sensitive single-molecule techniques to investigate the interactions between protein aggregates and small molecules. He was raised up in Hong Kong. He then moved to London and pursued his MSci degree at Imperial College London with Professor Ramon Vil...
Dr Matthew Cheetham
Matthew currently works on the development of a sensitive assay for early diagnosis of neurodegenerative diseases from blood serum. He completed his PhD at the University of Leeds in 2012 with Prof. Steve Evans, looking at the manipulation of lipid membranes with electric fields. After this, he w...
Dr Debasis Banik
Debasis is a Marie Curie postdoctoral fellow in the Klenerman group and currently working on developing an imaging-based ultrasensitive assay to monitor the early events of T cell-tumour interaction and identify the protein re-organization at interface. In his previous role at the Vanderbilt Univ...
Dr John Danial
John is a postdoctoral research fellow designing and constructing high-throughput super resolution microscopy to characterize protein aggregates. Prior to joining the Klenerman lab at the University of Cambridge, John worked in the group of Professor Ana Garcia-Saez at the University of Tubingen ...
Dr Shekhar Kedia
Shekhar is a postdoctoral researcher in Prof. Klenerman's group. He completed his PhD in Neuroscience (2020) from the Indian Institute of Science (IISc), Bangalore, India and was awarded a gold medal for his thesis. His research interests lie in understanding the nanoscale triggers of neurodegene...
