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PRINCIPAL INVESTIGATOR

David Klenerman

Professor Sir David Klenerman

David Klenerman's research is focused on developing and applying biophysical methods to biological and biomedical problems. His work using fluorescence and scanning probe microscopy has provided new insights into a variety of biomolecular complexes as well as the processes of protein folding and misfolding. David has also developed techniques to image individual protein complexes on the surface of living cells to follow the processes occurring as the adaptive immune response is triggered. These methods are now being used to study neurodegenerative disease.

David is a research fellow at the Royal Society, a fellow at the Academy of Medical Sciences and a fellow at Christ's College.

POSTDOCTORAL RESEARCHERS

Postdoctoral Researches
Dr Arpan Dey

Dr Arpan Dey

Arpan is a postdoctoral researcher in the Klenerman Group. He completed his integrated PhD from the Tata Institute of Fundamental Research, Mumbai, India. Currently, he is trying to understand the effect of amyloid-induced immune responses in neurodegeneration. Apart...

Dr Evgenia Lobanova

Dr Evgenia Lobanova

Evgenia obtained her BSc degree in Physics from Moscow State University in 2012. In 2014, she received her MSc degree in Physics from the same university. Soon after graduation, Evgenia moved to Cardiff where in 2019 she completed her Ph...

Dr Jason Sang

Dr Jason Sang

Jason finished his undergraduate studies in Taiwan and subsequently received his PhD from the University of Cambridge (under the supervision of Professor David Klenerman), studying the mechanism of prion-like aggregation in vitro. He applied single-molecule fluoresce...

Dr Yu Zhang

Dr Yu Zhang

Yu is a post-doctoral researcher working on developing advanced single molecule techniques towards in-depth research of the molecular basis of major neurogenerative diseases. Before moving to Cambridge, where he worked under the joint supervision of Prof. David Klene...

Dr Ziwei Zhang

Dr Ziwei Zhang

Ziwei is a post-doctoral researcher on a joint-project between the Klenerman’s group and the Laue group in the Department of Biochemistry at Cambridge. He will be working on developing current light-sheet microscopes in the lab and then use them to perform 3D super-r...

Dr Debasis Banik

Dr Debasis Banik

Debasis is a Marie Curie postdoctoral fellow in the Klenerman group and currently working on developing an imaging-based ultrasensitive assay to monitor the early events of T cell-tumour interaction and identify the protein re-organization at interface. In his previo...

Dr Georg Meisl

Dr Georg Meisl

gm373@cam.ac.uk

Georg is a postdoctoral researcher developing mathematical models of protein aggregation and neurodegenerative disease. He received his Msc in Chemistry and his PhD in biophysical Chemistry from the University of Cambridge. Following this, he was a Ramon Jenkins Rese...

Dr Shekhar Kedia

Dr Shekhar Kedia

Shekhar is a postdoctoral researcher in Prof. Klenerman's group. He completed his PhD in Neuroscience (2020) from the Indian Institute of Science (IISc), Bangalore, India and was awarded a gold medal for his thesis. His research interests lie in understanding the nan...

Dr Yunzhao Wu

Dr Yunzhao Wu

Yunzhao is a post-doctoral researcher working on elucidating the mechanisms of p53 aggregation in cancer with super-resolution imaging. He graduated from Shanghai Jiao Tong University in 2017 and obtained his master’s degree at the University of Tokyo in 2019. In his...

PhD STUDENTS

PhD Students
Asher Dworkin

Asher Dworkin

Asher is a PhD student working on automation and processes in the study of neurodegenerative disease with imaging protein aggre...

Daniel Heraghty

Daniel Heraghty

Daniel's research focuses on investigating the mechanisms that underlie the initiation of signalling by immune receptors. Prior...

Elizabeth English

Elizabeth English

Lizzie is investigating aggregation in Alzheimer’s disease in her PhD. She uses single molecule techniques, including super-res...

Janice Kim

Janice Kim

jek71@cam.ac.uk

Janice is a PhD student investigating protein aggregation in Alzheimer’s disease, with a focus on tau aggregation in relation t...

Prasanna Suresh

Prasanna Suresh

Prassana is a PhD student, and will be working on imaging the molecular events leading to Toll-like receptor signalling as part...

Tomi Akingbade

Tomi Akingbade

Tomi is a PhD student and will be investigating the sensitised inflammatory response to protein aggregation in Alzheimer’s Dise...

Beatrix Huissoon

Beatrix Huissoon

Beatrix is a PhD student looking at amyloid beta aggregation and its involvement in the development of AD. She completed her un...

Dorothea Böken

Dorothea Böken

Dorothea’s work is focused on developing single-molecule methods to study Tau aggregates in biological samples, specifically us...

Florence Layburn

Florence Layburn

Florence is a PhD student investigating the role of soluble α-synuclein aggregates in Parkinson's disease. She works with post-...

Kailai Xiong

Kailai Xiong

kx245@cam.ac.uk

Kelly is a PhD student working on using single-molecule methods to study the role of misfolded protein aggregates in neurodegen...

Shih-Huan Huang

Shih-Huan Huang

Shih-Huan's research focuses on developing a theoretical framework to explain pathological data in neurodegenerative diseases, ...

Yuhao Cui

Yuhao Cui

yc598@cam.ac.uk

Yuhao is a PhD student working on single molecule studies of Toll-like receptor 4 signalling pathway. Prior to joining the Klen...

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