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PRINCIPAL INVESTIGATOR

David Klenerman

Professor Sir David Klenerman

David Klenerman's research is focused on developing and applying biophysical methods to biological and biomedical problems. His work using fluorescence and scanning probe microscopy has provided new insights into a variety of biomolecular complexes as well as the processes of protein folding and misfolding. David has also developed techniques to image individual protein complexes on the surface of living cells to follow the processes occurring as the adaptive immune response is triggered. These methods are now being used to study neurodegenerative disease.

David is a research fellow at the Royal Society, a fellow at the Academy of Medical Sciences and a fellow at Christ's College.

POSTDOCTORAL RESEARCHERS

Postdoctoral Researches
Dr Debasis Banik

Dr Debasis Banik

Debasis is a Marie Curie postdoctoral fellow in the Klenerman group and currently working on developing an imaging-based ultrasensitive assay to monitor the early events of T cell-tumour interaction and identify the protein re-organization at interface. In his previous role at the Vanderbilt Univ...

Dr Jason Sang

Dr Jason Sang

Jason finished his undergraduate studies in Taiwan and subsequently received his PhD from the University of Cambridge (under the supervision of Professor David Klenerman), studying the mechanism of prion-like aggregation in vitro. He applied single-molecule fluorescence techniques to directly obs...

Dr Yu Zhang

Dr Yu Zhang

I am a PhD student working on developing advanced single molecule techniques towards in-depth research of the molecular basis of major neurogenerative diseases. Before moving to Cambridge, where I work under the joint supervision of Prof. David Klenerman and Dr Steven Lee, I studied nanomaterials...

Dr Ziwei Zhang

Dr Ziwei Zhang

I am a PhD student on a joint-project between the Klenerman’s group and the Laue group in the Department of Biochemistry at Cambridge. I will be working on developing current light-sheet microscopes in the lab and then use them to perform 3D super-resolution imaging of proteins and other interest...

Dr Evgenia Lobanova

Dr Evgenia Lobanova

Evgenia obtained her BSc degree in Physics from Moscow State University in 2012. In 2014, she received her MSc degree in Physics from the same university. Soon after graduation, Evgenia moved to Cardiff where in 2019 she completed her PhD degree (Oct. 2015 – Oct. 201...

Dr Shekhar Kedia

Dr Shekhar Kedia

Shekhar is a postdoctoral researcher in Prof. Klenerman's group. He completed his PhD in Neuroscience (2020) from the Indian Institute of Science (IISc), Bangalore, India and was awarded a gold medal for his thesis. His research interests lie in understanding the nanoscale triggers of neurodegene...

Dr Yunzhao Wu

Dr Yunzhao Wu

I’m a Ph.D. student working on elucidating the mechanisms of p53 aggregation in cancer with super-resolution imaging. I graduated from Shanghai Jiao Tong University in 2017 and obtained my master’s degree at the University of Tokyo in 2019. In my spare time, I enjoy cooking Chinese food (especial...

PhD STUDENTS

PhD Students
Asher Dworkin

Asher Dworkin

I am a first year PhD student working on automation and processes in the study of neurodegenerative disease with imaging protein aggregates in human biofluid...

Daniel Heraghty

Daniel Heraghty

My research focuses on investigating the mechanisms that underlie the initiation of signalling by immune receptors. Prior to joining the lab, I completed my ...

Elizabeth English

Elizabeth English

Lizzie is investigating aggregation in Alzheimer’s disease in her PhD. She uses single molecule techniques, including super-resolution microscopy and Simoa, ...

Prasanna Suresh

Prasanna Suresh

I am a PhD student, and will be working on imaging the molecular events leading to Toll-like receptor signalling as part of the innate immune response. Prior...

Tomi Akingbade

Tomi Akingbade

I am a PhD student and will be investigating the sensitised inflammatory response to protein aggregation in Alzheimer’s Disease. I completed my MSc in Neuros...

Beatrix Huissoon

Beatrix Huissoon

I’m a first year PhD student looking at amyloid beta aggregation and its involvement in the development of AD. I completed my undergraduate degree at Cambrid...

Dorothea Böken

Dorothea Böken

Dorothea’s work is focused on developing single-molecule methods to study Tau aggregates in biological samples, specifically using high resolution imaging te...

Florence Layburn

Florence Layburn

Florence is a first-year PhD student investigating α-synuclein aggregation in Parkinson's disease, with an emphasis on human brain tissue analysis. Florence ...

Shih-Huan Huang

Shih-Huan Huang

My research focuses on developing a theoretical framework to explain pathological data in neurodegenerative diseases, including progressive supranuclear pals...

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