Publications
Inhibiting the Ca2+ influx induced by human CSF
2017
A Drews, S De, P Flagmeier, DC Wirthensohn, W-H Chen, DR Whiten, M Rodrigues, C Vincke, S Muyldermans, RW Paterson, CF Slattery, NC Fox, JM Schott, H Zetterberg, CM Dobson, S Gandhi, D Klenerman
Cell reports
Absolute Quantification of Amyloid Propagons by Digital Microfluidics.
2017
M Pfammatter, M Andreasen, G Meisl, CG Taylor, J Adamcik, S Bolisetty, A Sánchez-Ferrer, D Klenerman, CM Dobson, R Mezzenga, TPJ Knowles, A Aguzzi, S Hornemann
Anal Chem
Nanopore extended field-effect transistor for selective single-molecule biosensing.
2017
R Ren, Y Zhang, BP Nadappuram, B Akpinar, D Klenerman, AP Ivanov, JB Edel, Y Korchev
Nature communications
Receptor Quaternary Organization Explains G Protein-Coupled Receptor Family Structure.
2017
JH Felce, SL Latty, RG Knox, SR Mattick, Y Lui, SF Lee, D Klenerman, SJ Davis
Cell Rep
Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species
2017
M Iljina, L Hong, MH Horrocks, MH Ludtmann, ML Choi, CD Hughes, FS Ruggeri, T Guilliams, AK Buell, J-E Lee, S Gandhi, SF Lee, CE Bryant, M Vendruscolo, TPJ Knowles, CM Dobson, E De Genst, D Klenerman
BMC biology
Ultrasensitive Measurement of Ca2+Influx into Lipid Vesicles Induced by Protein Aggregates
2017
P Flagmeier, S De, DC Wirthensohn, SF Lee, C Vincke, S Muyldermans, TPJ Knowles, S Gandhi, CM Dobson, D Klenerman
Angewandte Chemie International Edition
Three-Dimensional Super-Resolution in Eukaryotic Cells Using the Double-Helix Point Spread Function
2017
AR Carr, A Ponjavic, S Basu, J McColl, AM Santos, S Davis, ED Laue, D Klenerman, SF Lee
Biophys J
3D structures of individual mammalian genomes studied by single-cell Hi-C
2017
TJ Stevens, D Lando, S Basu, LP Atkinson, Y Cao, SF Lee, M Leeb, KJ Wohlfahrt, W Boucher, A O'Shaughnessy-Kirwan, J Cramard, AJ Faure, M Ralser, E Blanco, L Morey, M Sansó, MGS Palayret, B Lehner, L Di Croce, A Wutz, B Hendrich, D Klenerman, ED Laue
Nature
Direct Modulation of the Mitochondrial Permeability Transition Pore by Oligomeric Alpha-Synuclein Causes Toxicity in PD
2017
M Ludtmann, P Angelova, M-L Choi, M Horrocks, A Baev, D Little, M Devine, P Gissen, E Pavlov, D Klenerman, A Abramov, S Gandhi
Biophysical Journal
Ultrasensitive Measurement of Ca2+ Influx into Lipid Vesicles Induced by Protein Aggregates
2017
P Flagmeier, S De, DC Wirthensohn, SF Lee, C Vincke, S Muyldermans, TPJ Knowles, S Gandhi, CM Dobson, D Klenerman
Angewandte Chemie